Predictors of taking adherence
Predictor of dosing adherence | Coefficient (dimensionless) | p-value |
Univariate analyses | ||
Individual predictors measured only at baseline | ||
Age | 0.88 | 0.63 |
Marital status | −0.23 | 0.85 |
Health literacy | 0.00 | 1 |
Individual predictors measured longitudinally with time as covariate | ||
Time | −1.23 | 0.01 |
Intention to be adherent | −1.89 | 0.52 |
Time | −0.97 | 0.04 |
Number of side-effects reported | −0.55 | 0.57 |
Time | −0.96 | 0.04 |
Self-reported omission of pirfenidone | −1.41 | 0.02* |
Time | Not converged | |
Depression | ||
Time | −1.02 | 0.04 |
Barriers to adherence | −0.43 | 0.43 |
Time | −1.05 | 0.11 |
Knowledge about pirfenidone | 2.12 | 0.03* |
Prediction models (multivariate analyses) | ||
Model with predictors measured only at baseline | ||
Age | 1.12 | 0.57 |
Marital status | −0.37 | 0.78 |
Health literacy | 0.01 | 0.99 |
Model with predictors measured longitudinally | ||
Time | −1.21 | 0.04* |
Intention to be adherent | Not selected | |
Number of side-effects reported | Not selected | |
Self-reported omission of pirfenidone | −1.60 | 0.02* |
Depression | 0.04 | 0.98 |
Barriers to adherence | Not selected | |
Knowledge about pirfenidone | Not selected |
The variables which were not selected did not sufficiently improve the quality of the model. *: significance at the 0.05 level.