TABLE 3

Seasonal distribution of immune-related adverse event (IRAE) occurrence

Before propensity score matchingAfter propensity score matching#
nFV-positive (n=67)FV-negative (n=55)Combined (n=122)p-valuenFV-positive (n=50)FV-negative (n=55)Combined (n=105)p-value
Season of IRAEs1220.6201050.464
 Spring15 (22)9 (16)24 (20)12 (24)9 (16)21 (20)
 Summer17 (25)16 (29)33 (27)15 (30)16 (29)31 (30)
 Fall12 (18)14 (25)26 (21)7 (14)14 (25)21 (20)
 Winter23 (35)16 (30)39 (32)16 (32)16 (30)32 (30)
Influenza season of IRAEs1220.7991050.382
 Fall/winter35 (52)30 (55)65 (53)23 (46)30 (55)53 (50)
 Spring/  summer32 (48)25 (45)57 (47)27 (54)25 (45)52 (50)

Data are presented as n (%), unless otherwise stated. FV: influenza vaccination. #: one of the five propensity score matching models run after multiple imputations (the numbers varied very slightly among the five runs).