Cardiac catheterisation data at presentation
| n | Syncope at diagnosis# | n | Syncope on medication¶,+ | n | Non-syncope§ | p-value | |
| Baseline | |||||||
| Mean RAP mmHg | 7 (5–10) | 7 (6–10) | 7 (6–9) | 0.86 | |||
| Mean PAP mmHg | 53 (37–65) | 66.5 (51.8–72) | 48.5 (36–64) | 0.18 | |||
| sPAP/sSAP | 0.80 (0.50–0.99) | 0.83 (0.76–1.10) | 66 | 0.75 (0.50–0.95) | 0.47 | ||
| PVRi WU·m2 | 13.7 (8.8–22.0) | 20.1 (9.2–25.1) | 66 | 9.05 (5.3–14.5) | 0.04 | ||
| Rp/Rs | 30 | 0.7 (0.5–1) | 5 | 0.7 (0.3–1.5) | 59 | 0.6 (0.33–0.94) | 0.42 |
| CI L·min−1·m−2 | 3.0 (2.2–3.8) | 2.8 (2.5–3.2) | 66 | 3.5 (2.5–4.2) | 0.19 | ||
| AVT with iNO | 5 | 64 | |||||
| Mean RAP mmHg | 25 | 6 (4–8.5) | 3 | 7 (2–8) | 44 | 7 (6–8.5) | |
| Mean PAP mmHg | 35 | 38 (27–60) | 63 (53–66.5) | 37.5 (28–56.5) | 0.15 | ||
| sPAP/sSAP | 34 | 0.60 (0.40–0.92) | 0.77 (0.67–1.16) | 59 | 0.65 (0.46–0.89) | 0.30 | |
| PVRi WU·m2 | 33 | 9.3 (5.1–17.3) | 15.1 (11.9–19.5) | 61 | 6.5 (3.7–11) | 0.02 | |
| Rp/Rs | 21 | 0.46 (0.29–0.72) | N/A | 33 | 0.45 (0.21–0.83) | 0.99 | |
| CI L·min−1·m−2 | 33 | 3.2 (2.4–3.8) | 3.1 (2.7–3.8) | 58 | 3.6 (2.6–4.6) | 0.18 | |
| AVT responders (Barst) | 14 (40) | 0 | 15 (22) | 0.047 | |||
| AVT responders (Sitbon) | 8 (23) | 0 | 9 (13) | 0.27 |
Data are expressed as median (interquartile range) or n (%). Bold p-values represent statistically significant differences. n: number of patients; RAP: right atrial pressure; PAP: pulmonary artery pressure; sPAP/sSAP: ratio of pulmonary artery/systemic arterial systolic pressure; PVRi: indexed pulmonary vascular resistance; Rp/Rs: ratio of pulmonary vascular resistance/systemic vascular resistance; CI: cardiac index; AVT: acute vasodilator testing; iNO: inhaled nitric oxide. #: n=36; ¶: n=6; +: one patient with syncope on medication did not have a catheterisation available from the time of diagnosis; §: n=67.