TABLE 4

Catheterisation data with acute vasodilator testing (AVT) for syncope patient responders versus non-responders using Sitbon criteria

nAVT responders#nAVT negative with syncope at diagnosisnAVT negative with syncope on medications+p-value
Room air
 Mean RAP mmHg8 (1–16)7 (5–9)9 (8–10)0.33
 Mean PAP mmHg52 (41–66)54.5 (32–69.8)67 (61–81)0.15
 PVRi WU·m219.5 (11.8–23.7)14.2 (8.2–24.5)620.0 (7.8–26.3)0.67
 Rp/Rs60.7 (0.6–0.8)250.9 (0.5–1)61.3 (0.7–2.4)0.22
 CI L·min−1·m−22.3 (1.8–3.2)273.1 (2.3–3.8)3.8 (2.2–4.4)0.15
AVT with iNO
 Mean RAP mmHg46 (3–9)206.5 (5–8.8)69.5 (7.3–10.3)0.13
 Mean PAP mmHg29 (28–31)52.5 (26.3–74.8)64 (61–82)0.01
 PVRi WU·m257.9 (6–8)13.2 (4.7–20.9)522.5 (7.5–26.9)0.22
 Rp/Rs30.4 (0.2–0.4)170.7 (0.3–1)51.1 (0.5–2.3)
 CI L·min−1·m−23.1 (2.6–4.4)273.4 (2.3–3.8)3.4 (2.4–4.2)0.73

Data are expressed as median (interquartile range). Bold p-value represents statistically significant difference between AVT responders and AVT negative by Sitbon criteria. RAP: right atrial pressure; PAP: pulmonary artery pressure; PVRi: indexed pulmonary vascular resistance; Rp/Rs: ratio of pulmonary vascular resistance/systemic vascular resistance; CI: cardiac index; iNO: inhaled nitric oxide. #: n=7; : n=28; +: n=7.