Catheterisation data with acute vasodilator testing (AVT) for syncope patient responders versus non-responders using Sitbon criteria
| n | AVT responders# | n | AVT negative with syncope at diagnosis¶ | n | AVT negative with syncope on medications+ | p-value | |
| Room air | |||||||
| Mean RAP mmHg | 8 (1–16) | 7 (5–9) | 9 (8–10) | 0.33 | |||
| Mean PAP mmHg | 52 (41–66) | 54.5 (32–69.8) | 67 (61–81) | 0.15 | |||
| PVRi WU·m2 | 19.5 (11.8–23.7) | 14.2 (8.2–24.5) | 6 | 20.0 (7.8–26.3) | 0.67 | ||
| Rp/Rs | 6 | 0.7 (0.6–0.8) | 25 | 0.9 (0.5–1) | 6 | 1.3 (0.7–2.4) | 0.22 |
| CI L·min−1·m−2 | 2.3 (1.8–3.2) | 27 | 3.1 (2.3–3.8) | 3.8 (2.2–4.4) | 0.15 | ||
| AVT with iNO | |||||||
| Mean RAP mmHg | 4 | 6 (3–9) | 20 | 6.5 (5–8.8) | 6 | 9.5 (7.3–10.3) | 0.13 |
| Mean PAP mmHg | 29 (28–31) | 52.5 (26.3–74.8) | 64 (61–82) | 0.01 | |||
| PVRi WU·m2 | 5 | 7.9 (6–8) | 13.2 (4.7–20.9) | 5 | 22.5 (7.5–26.9) | 0.22 | |
| Rp/Rs | 3 | 0.4 (0.2–0.4) | 17 | 0.7 (0.3–1) | 5 | 1.1 (0.5–2.3) | |
| CI L·min−1·m−2 | 3.1 (2.6–4.4) | 27 | 3.4 (2.3–3.8) | 3.4 (2.4–4.2) | 0.73 |
Data are expressed as median (interquartile range). Bold p-value represents statistically significant difference between AVT responders and AVT negative by Sitbon criteria. RAP: right atrial pressure; PAP: pulmonary artery pressure; PVRi: indexed pulmonary vascular resistance; Rp/Rs: ratio of pulmonary vascular resistance/systemic vascular resistance; CI: cardiac index; iNO: inhaled nitric oxide. #: n=7; ¶: n=28; +: n=7.