Cardiac catheterisation data with acute vasodilator testing for idiopathic pulmonary arterial hypertension patients
n | Syncope# | n | Non-syncope¶ | p-value | |
Baseline | |||||
Mean RAP mmHg | 7 (5–10) | 6 (5–8) | 0.45 | ||
Mean PAP mmHg | 54 (40–69) | 52 (37–76) | 0.90 | ||
sPAP/sSAP | 0.81 (0.58–1.00) | 0.84 (0.55–1.10) | 0.74 | ||
PVRi WU·m2 | 16.7 (9.3–24.8) | 11.0 (5.5–20.2) | 0.10 | ||
Rp/Rs | 28 | 0.75 (0.60–1.00) | 31 | 0.7 (0.40–1.10) | 0.51 |
CI L·min−1·m−2 | 2.7 (2.0–3.4) | 34 | 3.55 (2.8–4.6) | 0.0047 | |
AVT with iNO | 34 | | |||
Mean RAP mmHg | 24 | 7 (4.5–8.5) | 27 | 6 (5–8) | 0.72 |
Mean PAP mmHg | 44 (27–64) | 41 (31–57) | 0.88 | ||
sPAP/sSAP | 33 | 0.70 (0.40–0.93) | 33 | 0.70 (0.46–0.91) | 0.63 |
PVRi WU·m2 | 32 | 13.2 (5.7–18.9) | 33 | 8.1 (3.6–12.2) | 0.037 |
Rp/Rs | 18 | 0.50 (0.30–0.72) | 19 | 0.45 (0.25–0.90) | 0.93 |
CI L·min−1·m−2 | 33 | 3.3 (2.5–3.7) | 33 | 3.8 (2.7–5.3) | 0.013 |
AVT responders (Barst) | 12 (35) | 8 (23) | 0.19 | ||
AVT responders (Sitbon) | 6 (18) | 5 (14) | 0.70 |
Data are expressed as median (interquartile range) or n (%). Bold p-values represent statistically significant differences. n: number of patients; RAP: right atrial pressure; PAP: pulmonary artery pressure; sPAP/sSAP: ratio of pulmonary artery/systemic arterial systolic pressure; PVRi: indexed pulmonary vascular resistance; Rp/Rs: ratio of pulmonary vascular resistance/systemic vascular resistance; CI: cardiac index; AVT: acute vasodilator testing; iNO: inhaled nitric oxide. #: n=34; ¶: n=35.