TABLE 6

Cardiac catheterisation data with acute vasodilator testing for idiopathic pulmonary arterial hypertension patients

nSyncope#nNon-syncopep-value
Baseline
 Mean RAP mmHg7 (5–10)6 (5–8)0.45
 Mean PAP mmHg54 (40–69)52 (37–76)0.90
 sPAP/sSAP0.81 (0.58–1.00)0.84 (0.55–1.10)0.74
 PVRi WU·m216.7 (9.3–24.8)11.0 (5.5–20.2)0.10
 Rp/Rs280.75 (0.60–1.00)310.7 (0.40–1.10)0.51
 CI L·min−1·m−22.7 (2.0–3.4)343.55 (2.8–4.6)0.0047
AVT with iNO34
 Mean RAP mmHg247 (4.5–8.5)276 (5–8)0.72
 Mean PAP mmHg44 (27–64)41 (31–57)0.88
 sPAP/sSAP330.70 (0.40–0.93)330.70 (0.46–0.91)0.63
 PVRi WU·m23213.2 (5.7–18.9)338.1 (3.6–12.2)0.037
 Rp/Rs180.50 (0.30–0.72)190.45 (0.25–0.90)0.93
 CI L·min−1·m−2333.3 (2.5–3.7)333.8 (2.7–5.3)0.013
AVT responders (Barst)12 (35)8 (23)0.19
AVT responders (Sitbon)6 (18)5 (14)0.70

Data are expressed as median (interquartile range) or n (%). Bold p-values represent statistically significant differences. n: number of patients; RAP: right atrial pressure; PAP: pulmonary artery pressure; sPAP/sSAP: ratio of pulmonary artery/systemic arterial systolic pressure; PVRi: indexed pulmonary vascular resistance; Rp/Rs: ratio of pulmonary vascular resistance/systemic vascular resistance; CI: cardiac index; AVT: acute vasodilator testing; iNO: inhaled nitric oxide. #: n=34; : n=35.