TABLE 2

Exercise tolerance and functional capacity

	Controls (n=15)	ILD (n=36)	p-value	ILD subgroups
	Controls (n=15)	ILD (n=36)	p-value	Robust (n=8)	Pre-frail (n=19)	Frail (n=9)
6MWT
Distance (m)	615±83	476±94	<0.0001	570±89^a	477±73^a	389±50^b
Distance (% pred)	124±15	101±18	<0.0001	118±11^a	100±15^b	87±16^b
End-test saturation (%)	95±4	85±6	<0.0001	86±6^a	85±6^a	85±9^a
1STS test
Repetitions (n)	30±7	21±4	<0.0001	26±2^a	21±3^b	17±3^c
End-test saturation (%)	96±2	89±5	<0.0001	89±5^a	90±5^a	88±4^a
5TSTS test time (s)	9.9±2.4	12.9±3.3	0.0019	10.3±1.6^a	13.0±2.6^b	15.0±4.3^b
SPPB total score	11.6±0.7	10.5±1.2	0.0007	11.4±0.7^a	10.5±0.9^a	9.7±1.6^a

Data are presented as mean±sd, unless otherwise stated. ILD: interstitial lung disease; 6MWT: 6-min walk test; 1STS: 1-min sit-to-stand; 5TSTS: 5 times sit-to-stand; SPPB: Short Physical Performance Battery. Different superscript letters indicate a statistically significant difference (p<0.05) between subgroups of patients with ILD such that groups with the same superscript letter are statistically similar but different from groups with a different superscript letter.