TABLE 2

Laboratory characteristics of granulomatous lymphocytic interstitial lung disease patients

Laboratory characteristicAcute steroidChronic MMF±corticosteroidsImmunoglobulin replacement
Serum immunoglobulin levels prior to period under study g·L−1
 IgG9.70 (8.30–10.40)8.00 (6.70–11.15)10.15 (6.60–14.38)
 IgA0.05 (0.05–0.10)0.05 (0.05–0.50)0.05 (0.01–0.16)
 IgM0.70 (0.50–1.30)0.70 (0.08–2.70)0.15 (0.06–0.28)
Trough immunoglobulin levels during period under study g·L−1
 IgG9.50 (8.93–11.60)10.70 (10.20–11.90)10.55 (10.05–12.70)
 IgA0.05 (0.04–0.16)0.05 (0.05–0.50)0.05 (0.05–0.31)
 IgM0.30 (0.16–0.90)0.30 (0.05–1.30)0.05 (0.05–0.24)
Lymphocyte subsets count prior to period under study ×109 per L
 Lymphocyte count1.09 (0.85–1.21)1.32 (0.68–1.70)1.07 (0.72–2.03)
 CD30.96 (0.82–1.01)1.01 (0.55–1.28)0.81 (0.55–1.33)
 CD40.59 (0.35–0.73)0.44 (0.28–0.77)0.61 (0.42–0.71)
 CD80.25 (0.20–0.42)0.35 (0.22–0.63)0.14 (0.09–0.76)
 CD190.04 (0.02–0.09)0.20 (0.10–0.23)0.15 (0.10–0.39)
 CD16+CD560.08 (0.03–0.38)0.08 (0.02–0.13)0.08 (0.05–0.12)
Lymphocyte subsets count during period under study ×109 per L
 Lymphocyte count0.78 (0.43–1.17)1.13 (0.55–1.87)0.60 (0.28–1.13)
 CD30.66 (0.39–0.98)0.88 (0.48–1.29)0.40 (0.19–0.93)
 CD40.32 (0.22–0.65)0.43 (0.27–0.74)0.35 (0.18–0.38)
 CD80.24 (0.18–0.29)0.29 (0.17–0.59)0.06 (0.03–0.51)
 CD190.03 (0.01–0.06)0.16 (0.02–0.38)0.10 (0.03–0.16)
 CD16+CD560.05 (0.02–0.11)0.06 (0.04–0.18)0.04 (0.02–0.06)
CVID EUROClass
 smB+21Lo53#
 smB+21norm11
 smB-21Lo23
 B-1

Data are presented as median (interquartile range). MMF: mycophenolate mofetil; CVID: common variable immunodeficiency disorder. #: two patients were also in the acute steroid group.