TABLE 4

Association between ΔBMI/y and annual decline in lung function after adjusting for other factors among BMI groups

ΔBMI/y
Normal weightOverweight/obese
B95% confidence intervalB95% confidence interval
ΔFEV1pp/y−0.356(−0.663– −0.049)−0.747(−1.003– −0.491)
ΔFEV1mL/y−14.662(−24.903– −4.420)−24.809(−33.608– −16.010)
ΔFVCpp/y−0.102(−0.436–0.232)−0.719(−1.026– −0.413)
ΔFVCmL/y−10.091(−23.509–3.328)−34.422(−48.073– −20.772)
ΔFEV1/FVC/y−0.002(−0.004–0.000)−0.000(−0.002–0.002)

Significant values are given in bold. Normal weight: BMI 18.5–24.9; overweight/obese: BMI ≥25. Adjusting factors: sex, age, changes in smoking habits, pack-years, inhaled corticosteroid use, occupational gas, dust or fumes exposure at follow-up and original cohort. BMI: body mass index; FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity; B: β-coefficient from linear regression models; ΔBMI/y: annual BMI change; ΔFEV1pp/y: annual FEV1pp decline; ΔFVCpp/y: annual FVCpp decline; pp: per cent of predicted; ΔFEV1mL/y: annual FEV1mL decline; ΔFVCmL/y: annual FVCmL decline; ΔFEV1/FVC/y: annual FEV1/FVC decline.