TABLE 4

Multivariable hazard ratio (HR) model between adjustment variables and 5-year all-cause mortality

VariableHR (95% CI)p-value
mets=0ref-
mets=11.06 (0.99–1.13)0.085
genderFemaleref-
genderMale1.33 (1.27–1.38)<0.001
age1.07 (1.07–1.07)<0.001
ethnicityWhiteref-
ethnicityBlack0.63 (0.42–0.93)0.020
ethnicityMixed_Other0.70 (0.55–0.90)0.005
ethnicitySouth Asian0.99 (0.70–1.41)0.970
ethnicityUnknown0.84 (0.72–0.97)0.020
smokingNonref-
smokingEx1.17 (1.10–1.26)<0.001
smokingCurrent1.75 (1.62–1.89)<0.001
smokingMissing1.16 (1.00–1.35)0.044
imd1ref-
imd21.05 (0.98–1.12)0.190
imd31.06 (0.99–1.14)0.102
imd41.05 (0.98–1.12)0.193
imd51.13 (1.05–1.20)<0.001
fev1pp0.99 (0.99–0.99)<0.001
n_exacs1.08 (1.06–1.10)<0.001
mrc1ref-
mrc21.21 (1.12–1.29)<0.001
mrc31.53 (1.42–1.64)<0.001
mrc41.89 (1.75–2.04)<0.001
mrc52.88 (2.57–3.22)<0.001
liver1.53 (1.36–1.72)<0.001
kidney1.25 (1.19–1.32)<0.001
psych1.41 (1.32–1.51)<0.001
frail1.26 (1.15–1.38)<0.001
asthma0.93 (0.89–0.97)<0.001
cvd1.44 (1.37–1.51)<0.001
mskel1.02 (0.98–1.07)0.350
gerd0.99 (0.91–1.06)0.700

Variables highlighted in bold are associated with 5-year all-cause mortality.