TABLE 3

Factors associated with death at 1 year in patients with unresected NSCLC: the CAP-Centre study

Potential risk factors of death at 1 year – patients with unresected NSCLC (n=360)Hazard ratio95% confidence interval
General characteristics
Age ≥65 years1.2(0.8–1.6)
Male1.0(0.7–1.5)
PS >12.1(1.5–3.0)
Histology
  Adenocarcinomaref
  Squamous cell carcinoma1.6(1.1–2.4)
  Undifferentiated carcinoma2.0(1.3–3.1)
  Others1.4(0.6–2.9)
Metastatic stage2.4(1.6–3.8)
Healthcare pathway
No immunotherapy1.8(1.3–2.7)
No targeted therapy2.5(1.3–4.9)
No radiotherapy2.8(1.7–4.7)
Administrative department of the first healthcare facility
  A1.1(0.5–2.3)
  B1.9(1.1–3.3)
  C0.8(0.4–2.0)
  Dref
  E1.3(0.6–2.5)
  F0.8(0.6–1.3)
  Outside of the CVL region1.7(0.7–3.8)
Nature of the first healthcare facility
  Teaching hospitalref
  Public hospital0.8(0.5–1.3)
  Private hospital0.5(0.4–0.8)
Time interval between diagnostic imaging and first treatment <49 days#1.5(1.1–2.1)

NSCLC: nonsmall cell lung cancer; PS: performance status; CVL: Centre-Val de Loire. #: 49 days corresponded to the median time interval between diagnostic imaging and first treatment.