TABLE 5

Selected interferon-γ release assay performance with different models, considering borderline results

SpecificitySensitivityNPVPPV
Binary analysis excluding borderline results93.96 (93.09–94.75)54.55 (40.55 −68.03)99.20 (98.83–99.48)13.04 (8.98 −18.09)
Borderline results regarded as positive91.31 (90.32–92.24)56.14 (42.36–69.26)99.20 (98.83–99.48)9.76 (6.77–13.49)
Borderline results regarded as negative94.13 (93.29–94.90)52.63 (38.97–66.02)99.17 (98.79–99.45)13.04 (8.98–18.09)

Data are presented as % (95% CI); data encompass only patients on biologics. NPV: negative predictive value; PPV: positive predictive value.