Selected interferon-γ release assay performance with different models, considering borderline results
Specificity | Sensitivity | NPV | PPV | |
Binary analysis excluding borderline results | 93.96 (93.09–94.75) | 54.55 (40.55 −68.03) | 99.20 (98.83–99.48) | 13.04 (8.98 −18.09) |
Borderline results regarded as positive | 91.31 (90.32–92.24) | 56.14 (42.36–69.26) | 99.20 (98.83–99.48) | 9.76 (6.77–13.49) |
Borderline results regarded as negative | 94.13 (93.29–94.90) | 52.63 (38.97–66.02) | 99.17 (98.79–99.45) | 13.04 (8.98–18.09) |
Data are presented as % (95% CI); data encompass only patients on biologics. NPV: negative predictive value; PPV: positive predictive value.