Baseline demographics for the entire cohort (n=121) #
| Characteristic | % or mean±sd | ||||
| Sex, % male | 70.3 | ||||
| Age years | 46.0±15.7 | ||||
| Smoking status, current % | 0.0 | ||||
| BMI kg·m−2 | 26.7±3.7 | ||||
| FEV1 L | 3.5±1.0 | ||||
| FEV1 % predicted | 104.8±15.7 | ||||
| FEV1/FVC % | 78.0±6.4 | ||||
| Sputum characteristics | Median (range) | Mean±sd | Percentile | 95% CI | |
| 10th | 90th | ||||
| Sputum total cell count ×106·g−1 | 5.64 (0.99–37.00) | 8.68±7.99 | 2.07 | 21.96 | 6.66–10.69 |
| Sputum neutrophil % | 62.00 (4.00–97.25) | 55.20±24.47 | 16.30 | 82.50 | 50.79–59.60 |
| Sputum eosinophil % | 0.00 (0.00–3.50) | 0.43±0.79 | 0.00 | 1.45 | 0.27–0.60 |
| Sputum lymphocyte % | 0.50 (0.00–3.75) | 0.85±0.88 | 0.00 | 2.00 | 0.67–1.03 |
| Sputum macrophage % | 35.00 (0.25–91.50) | 39.37±22.67 | 12.85 | 73.40 | 34.65–44.10 |
| Sputum epithelial cells % | 3.25 (0.00–3.75) | 6.21±8.46 | 0.50 | 15.25 | 4.45–7.97 |
| Sputum neutrophil cell count ×106·g−1 | 3.11 (0.14–30.53) | 5.79±15.40 | 0.72 | 15.40 | 4.16–7.43 |
| Sputum eosinophil cell count ×106·g−1 | 0.00 (0.00–0.75) | 0.05±0.13 | 0.00 | 0.09 | 0.02–0.08 |
| Sputum lymphocyte cell count ×106·g−1 | 0.04 (0.00–0.75) | 0.07±0.12 | 0.00 | 0.17 | 0.04–0.10 |
| Sputum macrophage cell count ×106·g−1 | 1.72 (0.19–8.25) | 2.43±1.87 | 0.59 | 5.42 | 1.95–2.90 |
| Sputum epithelial cell count ×106·g−1 | 0.24 (0.00–1.40) | 0.34±0.31 | 0.04 | 0.77 | 0.26–0.42 |
Data presented as mean±sd or median (range) unless specified otherwise. BMI: body mass index; FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity. #: 30 subjects did not have full differential cell counts data available aside from neutrophil %; 58 subjects did not have absolute sputum counts available.