Multivariable regression models of forced expiratory volume in 1 s (FEV1) % pred in the cystic fibrosis (CF) group

ModelGroupModel ofAge (years)Chronic Pseudomonas aeruginosa#Sex (female)Sweat chloride (mmol·L−1)HNE ASL FRAPModel
1CFFEV1 % pred (n=25)−1.10.001−22.70.007−10.90.12−<0.0001145
2CFFEV1 % pred (n=10)−0.850.11−30.00.09−27.80.03−0.210.45−
3CFFEV1 % pred (n=10)−1.10.09−7.950.70−24.80.07−0.250.570.760.03142

MCC: mucociliary clearance; P. aeruginosa: Pseudomonas aeruginosa; HNE: human nasal epithelial; ASL: airway surface liquid; FRAP: fluorescence recovery after photobleaching. FEV1 % pred=β1(age)+β2(P. aeruginosa)+β3(sex)+β4(sweat chloride)+β5(FRAP)+β0. #: chronic P. aeruginosa is defined as two or more positive throat or sputum cultures in the previous year; : only a portion of the CF group had FRAP measurements available (n=10).