TABLE 3

Associations (odds ratio (95% confidence interval)) between risk factors in childhood and asthma by age at onset#

Age at asthma onset
≤8 years9–13 years14–19 years>19 years
Female sex0.74 (0.54–0.99)0.93 (0.66–1.29)1.84 (1.33–2.56)1.22 (0.78–1.91)
Family history of asthma3.30 (2.43–4.48)3.25 (2.31–4.57)1.55 (1.08–2.24)2.04 (1.25–3.34)
Low birthweight1.87 (1.04–3.36)1.24 (0.55–2.78)1.15 (0.54–2.44)2.12 (0.94–4.82)
Breastfeeding <3 months2.02 (1.45–2.81)0.63 (0.40–0.98)1.57 (1.10–2.23)1.75 (1.07–2.85)
Smoking during pregnancy1.30 (0.93–1.84)1.54 (1.05–2.25)1.33 (0.93–1.90)0.78 (0.45–1.35)
Any severe respiratory infection2.76 (1.95–3.90)1.31 (0.93–1.84)1.11 (0.80–1.52)1.06 (0.68–1.67)
Rhinoconjunctivitis6.55 (4.47–9.61)2.78 (1.68–4.59)1.48 (0.80–2.74)1.50 (0.61–3.65)
Eczema1.75 (1.29–2.37)1.30 (0.93–1.83)1.20 (0.86–1.66)0.87 (0.53–1.41)
Allergic sensitisation3.20 (2.16–4.74)2.92 (1.87–4.55)2.23 (1.45–3.43)1.95 (0.97–3.94)

#: analysed in a multivariable multinomial regression analysis, with never-asthma as reference.