TABLE 4

Estimated changes of forced vital capacity z-scores with birth cohort in the total population

MalesFemales
Birth cohortnCoefficient95% CIp-valuenCoefficient95% CIp-value
1894–1904469---640---
1905–19145170.00(−0.12–0.12)0.9907200.13(0.02–0.24)0.020
1915–19246740.14(0.03–0.26)0.0107900.28(0.18–0.39)<0.001
1925–193415520.43(0.32–0.54)<0.00115800.54(0.43–0.66)<0.001
1935–194421250.61(0.50–0.73)<0.0017200.53(0.41–0.65)<0.001
1945–195417 8380.60(0.48–0.72)<0.00110950.50(0.36–0.64)<0.001
1955–196472230.61(0.49–0.73)<0.0012500.50(0.32–0.68)<0.001
1965–19691330.70(0.50–0.90)<0.0011400.64(0.43–0.85)<0.001

Linear mixed-effect models with random effects at the survey level, adjusted for smoking status, pack-years, education, lung diseases and respiratory symptoms. Birth cohort reference category = 1894–1904. Z-scores calculated according to Global Lung Function Initiative (GLI-2012) equations.