Variables that correlated with therapeutic response to hypertonic saline (HS) in the cystic fibrosis group

Baseline MCCadjusted31.62−0.440.200.01
HNE ASL FRAP diffusion time−23.5211.230.550.04

MCCadjusted: mucociliary clearance adjusted based on aerosol distribution; HNE: human nasal epithelial; ASL: airway surface liquid; FRAP: fluorescence recovery after photobleaching. Therapeutic response (=β1 (listed variable)+β0) is the improvement in MCCadjusted after inhaling HS compared with a baseline measurement made after isotonic saline inhalation.