Variables that correlated with therapeutic response to hypertonic saline (HS) in the cystic fibrosis group
β0 | β1 | R2 | p-value | |
Baseline MCCadjusted | 31.62 | −0.44 | 0.20 | 0.01 |
HNE ASL FRAP diffusion time | −23.52 | 11.23 | 0.55 | 0.04 |
MCCadjusted: mucociliary clearance adjusted based on aerosol distribution; HNE: human nasal epithelial; ASL: airway surface liquid; FRAP: fluorescence recovery after photobleaching. Therapeutic response (=β1 (listed variable)+β0) is the improvement in MCCadjusted after inhaling HS compared with a baseline measurement made after isotonic saline inhalation.