General characteristics of study subjects

Subjects, n213
Age, years63.6±7.0
BMI, kg·m−226.2±5.1
FFMI, kg·m−217.0±2.4
mMRC dyspnoea grade2.1±1.1
Current smoker28
Smoking pack-years46±26
Long-term oxygen therapy17
FEV1, L1.40±0.54
FEV1, % predicted51.2±16.9
ITGV, % predicted148±33
DLCO, % predicted56±17
6MWD, m470±106
SGRQ, total score51.3±17.5
Updated BODE score2.9±2.5
Framingham 10-year risk, %9.4±6.7

Data are presented as mean±sd or %, unless otherwise stated. BMI: body mass index; FFMI: fat-free mass index; mMRC: modified Medical Research Council; FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity; ITGV: intrathoracic gas volume; DLCO: diffusion capacity of the lung for carbon monoxide; 6MWD: 6-min walk distance; SGRQ: St George's Respiratory Questionnaire; BODE: body mass index, obstruction, dyspnoea, exercise capacity index.