TABLE 3

Performance of each symptom intensity scale, spirometric indices and exhaled nitric oxide fraction (FENO) to diagnose asthma in the training cohort (n=166)

ThresholdAUC (95% CI)Sensitivity (%)Specificity (%)p-value AUC
Wheezing intensity score0.50.67 (0.59–0.76)78 (69–86)54 (41–67)0.0002
Dyspnoea intensity score2.50.56 (0.46–0.64)38 (29–48)69 (56–80)0.2485
Cough intensity score0.50.53 (0.44–0.62)88 (80–93)20 (11–32)0.5410
Airway secretion intensity score0.50.56 (0.47–0.65)75 (66–83)34 (23–48)0.1847
Chest tightness intensity score2.50.51 (0.42–0.60)28 (19–37)77 (65–87)0.8762
FEV1 (% pred)960.68 (0.60–0.77)71 (62–80)59 (46–71)<0.0001
FEV1/FVC (%)780.69 (0.61–0.77)54 (44–64)79 (66–88)<0.0001
FENO (ppb)330.56 (0.47–0.66)32 (23–43)83 (71–92)0.1839

FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity. Bold indicates statistical significance.