Noninvasive ventilation (NIV) parameters and monitoring at day 30 for adherent patients of the at-home NIV initiation subgroup
Day 30 | Corrected SpO2 | Noncorrected SpO2 | p-value | |
NIV parameters | ||||
Patients, n | 126 | 99 (79) | 21 (17) | |
IPAP (cmH20) | 12.1±1.97 | 12±1.9 | 12.8±2.29 | 0.118 |
EPAP (cmH20) | 6.86±1.52 | 6.75±1.47 | 7.75±1.37 | 0.006 |
Back-up respiratory rate (acts per minute) | 13.4±1.17 | 13.5±1.15 | 13.3±1.03 | 0.531 |
Rise time (ms) | 444±134 | 447±140 | 439±115 | 0.602 |
Trigger (L·min−1) | 5.96±0.57 | 5.95±0.64 | 6±0 | 0.736 |
Cycling (%IPF) | 23±5.39 | 22.7±5.47 | 24±5.53 | 0.345 |
tI min (s) | 0.674±0.67 | 0.698±0.7 | 0.6±0.16 | 0.566 |
tI max (s) | 1.8±0.3 | 1.80±0.3 | 1.81±0.31 | 0.862 |
Face mask | 121 (96) | 96 (97) | 18 (90) | 0.156 |
NIV monitoring | ||||
Days (n) | 29.5±3.07 | 29.6±3.18 | 28.6±2.58 | 0.169 |
Days without use | 1.57±1.57 | 1.55±3.45 | 0.286±0.72 | 0.099 |
Patients with fractional use | 3 (2) | 2 (2) | 1 (5) | 0.444 |
NIV use (h) | 7.58±1.50 | 7.45±1.48 | 8.17±1.36 | 0.043 |
VT (mL) | 426±88 | 420±80.9 | 456±113 | 0.099 |
Respiratory rate (acts per minute) | 16.2±5.55 | 16.3±2.62 | 15.4±1.79 | 0.131 |
Leaks (L·min−1) | 4.04±12.2 | 3.98±13.2 | 4.74±8.66 | 0.805 |
Leaks >24 L·min−1 | 4 (3) | 3 (3) | 1 (5) | 0.656 |
AHI | 6.33±9.71 | 5.63±8.38 | 10.1±14.9 | 0.066 |
AHI >10 | 24 (19) | 16 (16) | 6 (30) | 0.146 |
SpO2 assessment | ||||
SpO2 night-time <90 (%) | 3.62±7.01 | 1.38±1.56 | 14.2±11.8 | <0.001 |
There were six missing results. Data are presented as mean±sd or n (%) unless otherwise stated. AHI: apnoea-hypopnoea index; EPAP: expiratory positive airway pressure; IPAP: inspiratory positive airway pressure; IPF: inspiratory peak flow; SpO2: oxygen saturation measured by pulse oximetry; tI: inspiratory time; VT: tidal volume.