All | 1st quartile | 2nd quartile | 3rd quartile | 4th quartile | p-values | |
Participants n | 107 301 | 28 113 | 27 658 | 24 750 | 26 780 | |
Age years | 58 (48–68) | 53 (44–66) | 58 (48–68) | 60 (50–68) | 60 (52–68) | 0.0001 |
Women | 59 279 (55) | 16 418 (58) | 15 204 (55) | 13 178 (53) | 14 479 (54) | <0.0001 |
LDL cholesterol mmol·L−1 | 3.4±1.0 | 2.3±0.4 | 3.0±0.2 | 3.6±0.2 | 4.6±0.6 | <0.0001 |
Body mass index kg·m−2 | 26.2±4.2 | 25.1±4.2 | 26.0±4.3 | 26.5±4.2 | 27.1±4.2 | <0.0001 |
Never-smokers | 42 194 (42.0) | 11 664 (44.3) | 11 161 (43.1) | 9549 (41.2) | 9820 (39.1) | <0.0001 |
Light smokers (≤10 pack-years) | 20 980 (20.8) | 5931 (22.4) | 5547 (21.4) | 4701 (20.2) | 4801 (19.1) | <0.0001 |
Heavy smokers (>10 pack-years) | 39 192 (38.8) | 9230 (34.9) | 9635 (37.1) | 9389 (40.3) | 10 938 (43.4) | <0.0001 |
Cumulative smoking pack-years | 15.5 (6.0–30) | 13.8 (5.0–28.5) | 15.0 (5.6–30) | 16.4 (6.5–30.0) | 18.0 (7.5–32.0) | 0.0001 |
Lipid-lowering therapy | 12 922 (12.1) | 3250 (11.6) | 3176 (11.5) | 2598 (10.5) | 3898 (14.6) | <0.0001 |
Alcohol g·week−1 | 96 (48–180) | 96 (36–168) | 96 (48–180) | 96 (48–180) | 108 (48–192) | 0.0001 |
Physical inactivity | 51 486 (48.4) | 12 455 (44.7) | 12 977 (47.3) | 12 095 (49.3) | 13 959 (52.6) | <0.0001 |
FEV1 % predicted | 96.4±16.1 | 96.5±16.0 | 96.8±16.1 | 96.4±16.1 | 96.0±16.2 | <0.0001 |
FVC % predicted | 101.2±15.7 | 101.5±15.5 | 101.6±15.6 | 101.2±15.7 | 100.5±15.9 | <0.0001 |
FEV1/FVC | 76.8±7.7 | 77.0±7.9 | 76.8±7.7 | 76.5±7.6 | 76.8±7.5 | <0.0001 |
Data are presented as n (%) for categorical variables and mean±sd or median (interquartile range) for continuous variables depending on whether data were normally distributed. Cumulative smoking values are only from former and current smokers. FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity.