TABLE 1

Patient characteristics, intensive care unit (ICU) treatment strategies and treatment data

Patient characteristicsTotalSimple PITS/PTTSComplex PITS/PTTSp-value#
Patients2414 (58.3%)10 (41.7%)
Age, years55.5 (51–68.75)55.5 (50–64.5)58(53–69.5)0.52
Male12 (50%)6 (42.9%)6 (60%)0.68
Female12 (50%)8 (57.1%)4 (40%)
Never-smoker17 (71%)11 (78.6%)6 (60%)0.39
Active/former smoker7 (29%)3 (21.4%)4 (40%)
BMI, kg·m−2, mean±sd28.8±4.828.5±528.8±4.50.58
Underweight000
Normal weight6 (25%)4 (28.6%)2 (20%)0.63
Overweight13 (54.2%)6 (42.9%)7 (70%)0.24
Obese2 (8.3%)1 (7.1%)1 (10%)0.8
Extremely obese3 (12.5%)2 (14.2%)1 (10%)0.75
Comorbidities
 Arterial hypertension16 (67%)9 (64.3%)7 (70%)0.77
 Diabetes mellitus10 (41.7%)5 (35.7%)5 (50%)0.68
 Heart disease2 (8.3%)2 (14.2%)00.49
 Active malignancy3 (12.5%)2 (14.2%)1 (10%)0.75
 Chronic kidney disease1 (4.2%)1 (7.1%)0
ICU treatment characteristics
 Duration of MV, days12(10–22.5)10 (9–18.5)16 (12–24.75)0.14
 Duration of MV >14 days11 (45.8%)5 (35.7%)6 (60%)0.41
 Maximum duration of MV, days n505044
 Reintubation3 (8.3%)2 (14.2%)1 (10%)0.75
 Tracheotomy10 (41.7%)3 (21.4%)7 (70%)0.035
Patient presentation
 Stridor11 (45.8%)7 (50%)4 (40%)0.7
 Dyspnoea12 (50%)7 (50%)5 (50%)1
 Food aspiration1 (4.2%)01 (10%)0.42
 Time to symptom onset, days34 (14.5–60)42 (14.75–60)19.5 (7–48.75)0.38
 Time to PITS diagnosis, days15 (2–42)30 (11–75)8.5 (0.75–33)0.1
Initial PITS/PTTS treatment strategy
 Rigid bronchoscopy14 (58.3%)12 (85.7%)2 (20%)0.003
 Thoracic surgery7 (29.2%)1 (7.1%)6 (60%)0.009
 Tracheotomy1 (4.2%)01 (10%)0.42
 Lost to follow-up2 (8.3%)1 (7.1%)1 (10%)0.8

Data are presented as n (%) or median (interquartile range) unless otherwise stated. PITS: post-intubation tracheal stenosis; PTTS: post-tracheotomy tracheal stenosis; BMI: body mass index; MV: mechanical ventilation. #: Mann–Whitney, Chi-squared or Fisher's exact test as appropriate. Bold indicates statistically significant p-values.