TABLE 4

Top 10 proteins significantly different between two K-means clusters determined based on protein expression

ProteinUniProt IDAverage test statisticp-valueQ-value
Beclin-1Q14457−8.9607090.00010000.0035519
Hepatocyte nuclear factor 4-αP412356.5924310.00010000.0035519
Mothers against decapentaplegic homolog 3P840226.5906340.00010000.0035519
Ankyrin repeat domain-containing protein 1Q15327−4.9387200.00010000.0035519
NeurotriminQ9P121−5.4688400.00010000.0035519
Triple functional domain proteinO75962−4.3309470.00010000.0035519
RING finger protein 122Q9H9V47.6719310.00010000.0035519
Adhesion G-protein-coupled receptor F1Q5T60110.4907940.00010000.0035519
Calsequestrin-1P314157.9722400.00010000.0035519
TransaldolaseP378379.1389110.00010000.0035519

p-values determined by permutation testing. Average test statistic calculated by averaging the t-test statistic across aptamers that correspond to each protein.