Case | Control | Total | |
Patients n | 26 | 26 | 52 |
Sex n (%) | |||
Male | 20 (76.9) | 18 (69.2) | 38 (73.1) |
Female | 6 (23.1) | 8 (30.8) | 14 (26.9) |
Age years* | |||
Mean±sd | 59.6 (8.58) | 53.8 (7.30) | 56.7 (8.41) |
Median (range) | 58.0 (44.0–80.0) | 54.0 (42.0–76.0) | 56.0 (42.0–80.0) |
Ethnicity n (%) | |||
Black, non-Hispanic | 16 (61.5) | 12 (46.2) | 28 (53.8) |
White, Hispanic/Latino | 10 (38.5) | 13 (50.0) | 23 (44.2) |
Asian/Pacific Islander | 0 (0) | 1 (3.8) | 1 (1.9) |
Smoker n (%) | |||
Yes | 14 (53.8) | 14 (53.8) | 28 (53.8) |
Former | 9 (34.6) | 7 (26.9) | 16 (30.8) |
Never | 3 (11.5) | 5 (19.2) | 8 (15.4) |
Pack-years* | |||
Mean±sd | 31.1 (28.3) | 15.2 (13.7) | 23.1 (23.4) |
Median (range) | 29.6 (0–120) | 13.6 (0–38.0) | 17.2 (0–120) |
Receiving ART n (%) | |||
Yes | 24 (92.3) | 24 (92.3) | 48 (92.3) |
No | 2 (7.7) | 2 (7.7) | 4 (7.7) |
Viral load n (%) | |||
<50 copies | 12 (46.2) | 18 (69.2) | 30 (57.7) |
>50 copies | 2 (7.7) | 3 (11.5) | 5 (9.6) |
Missing | 12 (46.2) | 5 (19.2) | 17 (32.7) |
FEV1 % pred*** | |||
Mean±sd | 68.0 (15.9) | 104 (11.2) | 85.8 (22.6) |
Median (range) | 68.3 (21.0–90.4) | 102 (81.3–128) | 86.2 (21.0–128) |
FEV1 L | |||
Mean±sd | 2.07 (0.596) | 3.25 (0.746) | 2.66 (0.896) |
Median (range) | 2.09 (0.650–3.29) | 3.08 (1.95–4.77) | 2.59 (0.650–4.77) |
FEV1/FVC | |||
Mean±sd | 0.556 (0.113) | 0.795 (0.0567) | 0.676 (0.150) |
Median (range) | 0.590 (0.293–0.679) | 0.789 (0.689–0.905) | 0.684 (0.293–0.905) |
DLCO % pred*** | |||
Mean±sd | 71.6 (26.3) | 76.6 (23.1) | 74.2 (24.6) |
Median (range) | 67.6 (36.3–139) | 74.5 (14.4–117) | 74.5 (14.4–139) |
Missing n (%) | 6 (23.1) | 5 (19.2) | 11 (21.2) |
Cases and controls were matched based on age, smoking status and ART status. ART: antiretroviral treatment; FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity; DLCO: diffusing capacity of the lung for carbon monoxide. Asterisks denote variables that were significantly different between cases and controls: *: significance at the 0.05 level; ***: significance at the 0.001 level.