TABLE 3

Relationships between changes in peak oxygen consumption (VO2) and in 6-min walk distance (6MWD) as dependent variables, and changes in pulmonary vascular resistance (PVR) and pulmonary artery compliance (Cpa; calculated according to the pulse-pressure method)

Change in peak VO2Change in 6MWD
β estimate# (95% CI)p-valueβ estimate# (95% CI)p-value
PVR−0.39 (−0.74– −0.05)0.02−0.42 (−0.79– −0.04)0.03
 Gender0.10 (1.10–1.31)0.800.36 (1.03–0.31)0.28
 Weight0.13 (0.51–0.25)0.160.42 (0.14–0.84)0.14
 Height0.46 (0.13–1.05)0.120.11 (0.56–0.79)0.73
 Age0.09 (0.25–0.44)0.580.06 (0.44–0.33)0.76
Cpa0.02 (0.43–0.49)0.900.16 (0.24–0.55)0.42
 Gender0.83 (20.13–21.53)0.920.39 (1.15–0.37)0.30
 Weight−0.52 (−0.89– −0.07)0.020.19 (0.21–0.59)0.34
 Height0.52 (0.15–1.19)0.130.26 (0.49–1.00)0.50
 Age0.01 (0.38–0.36)0.950.13 (0.54–0.27)0.36

Adjustment was made to selected morphometric variables that may influence exercise capacity. Bold type represents statistical significance. #: coefficient that compares the strength of the effect of each individual independent variable (i.e. PVR, Cpa, gender, weight, height and age) to the dependent variables (i.e. peak VO2 and 6MWD).