TABLE 1

Baseline characteristics

Healthy32
 Female/male12/20
Age years43±15
Body mass index kg·m−223±2.6
SpO2 at rest %99±1
Pulmonary vascular disease22
Chronic thromboembolic pulmonary hypertension11
Pulmonary arterial hypertension11
Female/male8/14
Age years61±14
Body mass index kg·m−227.1±6
SpO2 at rest %95±3
Mean pulmonary arterial pressure mmHg35±9
Pulmonary arterial wedge pressure mmHg11±3
Pulmonary vascular resistance WU4.7±2.5
COPD20
 Female/male11/9
Age years65±6
Body mass index kg·m−227.1±6
SpO2 at rest %95±2
GOLD grade 1/2/3/44/11/4/1
FEV1 % pred64±18
FVC % pred107±17
FEV1/FVC0.5±0.1
Heart failure with preserved ejection fraction10
 Female/male5/5
Age years60±9
Body mass index kg·m−228±6
SpO2 at rest %98±2
Mean pulmonary arterial pressure mmHg37±14
Pulmonary arterial wedge pressure mmHg18±2
LVEF %63±5
Cyanotic congenital heart disease7
 Female/male4/3
Age years36±9
Body mass index kg·m−223±2
SpO2 at rest %87±6
Corrective heart surgery in childhood3

Data are presented as mean±sd or absolute numbers. SpO2: oxygen saturation by pulse oximetry; GOLD: Global Initiative for Chronic Obstructive Lung Disease; FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity; LVEF: left ventricular ejection fraction.