Cardiopulmonary exercise testing (CPET) variables obtained at peak exercise and variables measured during 6-min walk test (6MWT) before and after balloon pulmonary angioplasty (BPA)
| Pre-BPA | Post-BPA | p-value | |
| CPET | |||
| V′O2, L·min−1 | 1.11±0.35 | 1.30±0.33 | <0.001 |
| V′O2, mL·kg−1·min−1 | 14.5±3.8 | 17.1±4.1 | <0.001 |
| V′CO2, mL·min−1 | 1.21±0.44 | 1.41±0.42 | <0.001 |
| Workload, W | 73±26 | 85±29 | <0.001 |
| RER | 1.08±0.13 | 1.08±0.14 | 0.98 |
| Lactate, mmol·L−1 | 5.0±1.9 | 5.2±1.8 | 0.28 |
| Heart rate, beats·min−1 | 133±17 | 138±15 | 0.02 |
| V′E/V′CO2 | 57±17 | 47±11 | <0.001 |
| Physiological VD/VT, % | 39±10 | 33±10 | <0.001 |
| PaO2, mmHg | 61±10 | 69±14 | <0.001 |
| PaCO2, mmHg | 31±5 | 34±4 | <0.001 |
| PETCO2, mmHg | 24±6 | 28±5 | <0.001 |
| Borg dyspnoea score | 7.4±2.0 | 5.9±2.2 | 0.003 |
| Borg leg fatigue | 6.1±3.0 | 5.6±2.6 | 0.24 |
| 6MWT | |||
| 6MWD, m | 393±119 | 432±100 | <0.001 |
| Heart rate#, beats·min−1 | 114±21 | 112±13 | 0.55 |
| SpO2#, % | 87±5 | 88±4 | 0.09 |
| Nadir SpO2#, % | 86±5 | 87±5 | 0.15 |
| Borg dyspnoea score# | 4.4±2.1 | 3.0±2.0 | 0.002 |
| Borg leg fatigue# | 1.8±2.0 | 1.8±2.3 | 0.87 |
Data are presented as mean±sd, unless otherwise stated. Comparisons were made using the paired t-test. V′O2: oxygen consumption; V′CO2: carbon dioxide output; RER: respiratory exchange ratio; V′E: minute ventilation; VD/VT: dead space fraction of tidal volume; PaO2: oxygen arterial partial pressure; PaCO2: carbon dioxide arterial partial pressure; PETCO2: end-tidal carbon dioxide pressure; 6MWD: 6-min walk distance; SpO2: oxygen saturation measured by pulse oximetry. #: measured at end of 6MWT.