Baseline participant characteristics
| IMT (n=10) | Control (n=5) | |
| Demographics | ||
| Male, n (%) | 7 (70) | 4 (80) |
| Age, years | 63±6.6 | 56.6±10.8 |
| Weight, kg | 89±21.2 | 93.2±16.4 |
| Height, cm | 175±10.3 | 177±12.6 |
| BMI, kg·m−2 | 28.8±3.6 | 29.5±1.4 |
| BDI score, 0–12 scale | 6.5±1.8 | 7.6±1.7 |
| Left-side paralysis, n (%) | 4 (40) | 4 (80) |
| Pulmonary function | ||
| FVC, % predicted | 72±7 | 65±9 |
| FEV1, % predicted | 66±5 | 58±8 |
| FEV1/FVC, ratio | 0.71±0.08 | 0.74±0.09 |
| FVCsupine-FVCseated, % dif | −29±9 | −24±8 |
| IC, % predicted | 81±14 | 66±32 |
| TLC, % predicted | 79±38 | 75±35 |
| RV, % predicted | 107±54 | 105±49 |
| FRC, % predicted | 83±41 | 76±34 |
| TLCO, % predicted | 84±44 | 55±25 |
| KCO, % predicted | 117±61 | 97±43 |
| Respiratory muscle strength | ||
| PI,max, % predicted | 80±20 | 83±16 |
| PE,max, cmH2O, % predicted | 169±72 | 143±65 |
| Peak incremental exercise | ||
| Work rate, Watts | 134±40 | 163±64 |
| Work rate, % predicted | 95±19 | 101±19 |
| Heart rate, beats·min−1 | 130±47 | 127±62 |
| Heart rate, % predicted | 84±30 | 77±36 |
| VʹO2, L·min−1 | 2.0±0.6 | 2.5±1.4 |
| VʹO2, % predicted | 89±13 | 107±49 |
| VʹO2, L·min−1 | 2.1±0.6 | 2.8±1.5 |
| VʹE, L·min−1 | 63.4±17.9 | 74.2±38.5 |
| VʹE/MVV, % | 74±32 | 98±49 |
| VʹE/VʹCO2 | 30.9±3.6 | 27.1±12.3 |
| RER | 1.07±0.10 | 1.09±0.49 |
| O2 pulse, ml·beat−1 | 15.4±7.3 | 19.8±9.3 |
| SpO2, % | 95±40 | 91±41 |
| Dyspnoea, 0–10 scale | 8.0±1.7 | 9.8±0.4 |
| Leg effort, 0–10 scale | 7.6±1.9 | 6.2±3.9 |
| Reasons for stopping, n (% contribution): | ||
| Breathing discomfort | 7 (70) | 3 (60) |
| Leg discomfort | 1 (10) | 1 (20) |
| Combination | 2 (20) | 1 (20) |
Values represented number (percent) or mean±sd. BMI: body mass index; BDI: baseline dyspnoea index; FVC: forced vital capacity; FEV1: forced expiratory volume in 1 s; FRC: functional residual capacity; IC: inspiratory capacity; KCO: carbon monoxide transfer coefficient; MVV: maximal voluntary ventilation; O2 pulse: oxygen consumed per heart beat; PE,max: maximal expiratory pressure; PI,max: maximal inspiratory pressure; RER: respiratory exchange ratio; RV: residual volume; SpO2: peripheral oxygen saturation; TLC: total lung capacity; TLCO: transfer factor for carbon monoxide; V′CO2: carbon monoxide production; V′E: minute ventilation; V′E/V′CO2: ventilatory equivalent for carbon dioxide; V′O2: oxygen consumption.