Risk of dyspnoea in individuals with venous thromboembolism (VTE)# in the general population
| No VTE (n=97 388) | VTE | p-value¶ | Adjusted OR (95% CI)+ | Adjusted OR (95% CI)§ | |
| PEƒ | n=2273 | ||||
| Light dyspnoea | 3.2±0.1 | 8.2±0.6 | <0.001 | 2.1 (1.7–2.4) | 1.6 (1.4–2.0) |
| Moderate dyspnoea | 2.2±0.0 | 8.3±0.6 | <0.001 | 2.4 (2.0–2.8) | 2.1 (1.8–2.5) |
| Severe dyspnoea | 2.8±0.1 | 10.5±0.7 | <0.001 | 2.8 (2.4–3.3) | 2.4 (2.0–2.8) |
| DVT## | n=3718 | ||||
| Light dyspnoea | 3.2±0.1 | 6.3±0.4 | 0.007 | 1.6 (1.4–1.9) | 1.2 (1.05–1.4) |
| Moderate dyspnoea | 2.2±0.0 | 5.3±0.4 | 0.001 | 1.6 (1.4–1.9) | 1.3 (1.1–1.6) |
| Severe dyspnoea | 2.8±0.1 | 6.6±0.4 | <0.001 | 1.8 (1.5–2.1) | 1.3 (1.2–1.6) |
| VTE | n=5404 | ||||
| Light dyspnoea | 3.2±0.1 | 7.0±0.4 | <0.001 | 1.8 (1.6–2.0) | 1.4 (1.2–1.6) |
| Moderate dyspnoea | 2.2±0.0 | 6.1±0.3 | <0.001 | 1.8 (1.6–2.1) | 1.6 (1.4–1.8) |
| Severe dyspnoea | 2.8±0.1 | 7.7±0.4 | <0.001 | 2.1 (1.9–2.4) | 1.7 (1.5–1.9) |
Values are presented as mean±sem, unless otherwise stated. PE: pulmonary embolism; DVT: deep vein thrombosis. #: either PE or DVT; ¶: p-values for comparison with individuals without VTE on Pearson's Chi-squared test; +: adjusted for sex and age; §: adjusted for sex, age, smoking and body mass index; ƒ: International Classification of Diseases (ICD)-8: 450.99, 673.99; ICD-10: I26.0, I26.9, O88.2; ##: ICD-8: 451.00, 451.08–09, 451.90, 451.92, 671.01–03, 671.08–09; ICD-10: I80.1–3, O22.3, O87.1.