Risk of asthma by factor V Leiden and prothrombin G20210A genotype

SubjectsAsthma#Adjusted OR (95% CI)p-trendAdjusted OR (95% CI)+p-trend
No mutation91 4395.0±0.20.0020.002
Heterozygotes99815.7±0.2**1.1 (1.0–1.3)**1.1 (1.0–1.3)**
Homozygotes/compound heterozygotes3886.2±0.21.3 (0.8–1.9)1.2 (0.8–1.9)

Values are presented as n or prevalence±sd, unless otherwise stated. #: International Classification of Diseases (ICD)-8: 493; ICD-10: J45–J46; : adjusted for sex and age; +: adjusted for sex, age, smoking and body mass index. **: p<0.01 for comparison with individuals without mutations on Pearson's Chi-squared test or logistic regression analysis.