Risk of asthma by factor V Leiden and prothrombin G20210A genotype
| Subjects | Asthma# | Adjusted OR (95% CI)¶ | p-trend | Adjusted OR (95% CI)+ | p-trend | |
| No mutation | 91 439 | 5.0±0.2 | 0.002 | 0.002 | ||
| Heterozygotes | 9981 | 5.7±0.2** | 1.1 (1.0–1.3)** | 1.1 (1.0–1.3)** | ||
| Homozygotes/compound heterozygotes | 388 | 6.2±0.2 | 1.3 (0.8–1.9) | 1.2 (0.8–1.9) |
Values are presented as n or prevalence±sd, unless otherwise stated. #: International Classification of Diseases (ICD)-8: 493; ICD-10: J45–J46; ¶: adjusted for sex and age; +: adjusted for sex, age, smoking and body mass index. **: p<0.01 for comparison with individuals without mutations on Pearson's Chi-squared test or logistic regression analysis.