TABLE 2

Clinical course of patients with isolation of Mycobacterium simiae

PatientSexAge yearsDispositionClinical manifestationPulmonary radiologyATS criteria fulfilledOther NTM speciesNTM therapyOutcome
P1m37CFPulmonaryBronchiectasis, nodular changesyM. chimaeraClarithromycin, moxifloxacin, clofazimine, cotrimoxazoleCulture conversion, alive
P2m70MalignomaPulmonaryBronchiectasis, malignomanNAnCulture conversion, alive
P3m78MalignomaPulmonaryInfiltration, pleural effusionnNAnAlive
P4m63SLD (emphysema, bronchiectasis)PulmonaryBronchiectasis, carnificating pneumonianNAnAlive
P5f36CFPulmonaryBronchiectasisyM. abscessus, M. intracellulare, M. chelonaeClarithromycin, levofloxacin, linezolidCulture conversion, alive
P6m36CFPulmonaryBronchiectasis, infiltrationnM. abscessusnCulture conversion, alive
P7f41HIV CDC Stadium C3DisseminatedSlight emphysemaNANAClarithromycin/azithromycin, ethambutol, rifabutin, levofloxacin, cotrimoxazoleCulture conversion, alive

NTM: non-tuberculous mycobacterium; P: patient; CF: cystic fibrosis; SLD: structural lung disease; CDC: Centers for Disease Control and Prevention; NA: not applicable; m: male; f: female; y: yes; n: no.