Patient demographics and characteristics
| ASPEN cohort# | |
|---|---|
| Age years, mean±sd | 61.3±14.2 |
| ≥65 years, n (%) | 841 (50.0) |
| ≥75 years, n (%) | 262 (15.6) |
| Sex, n (%) | |
| Female | 1088 (64.7) |
| Race, n (%) | |
| White | 1235 (73.4) |
| Black or African American | 10 (0.6) |
| Asian | 189 (11.2) |
| American Indian or Alaska Native | 23 (1.4) |
| Native Hawaiian or Pacific Islander | 2 (0.1) |
| >1 race | 37 (2.2) |
| Not reported/unknown/other | 186 (11.1) |
| BMI kg·m−2, mean±sd | 25.5±5.1 |
| Smoking status/ever smoked, n (%) | |
| Never | 1169 (69.5) |
| Ex-smoker | 513 (30.5) |
| Pack-years smoked in ex-smokers, mean±sd | 16.3±20.5 |
| MRC dyspnoea score, n (%) | |
| 1–3 | 1604 (95.4) |
| 4 | 66 (3.9) |
| 5 | 12 (0.7) |
| Pseudomonas aeruginosa, n (%) | |
| Positive | 600 (35.7) |
| Exacerbations in prior 12 months, n (%) | |
| 2 | 1190 (70.7) |
| 3 or more | 492 (29.3) |
| BSI, mean±sd | 7.1±3.6 |
| Overall BSI score categories, n (%) | |
| ≤4 | 435 (25.9) |
| 5–8 | 714 (42.4) |
| ≥9 | 533 (31.7) |
| Eosinophil count (average cells·mm−3), mean±sd | 218.5±234.0 |
| Blood eosinophil, n (%) | |
| <300 cells·µL−1 | 1232 (73.2) |
| ≥300 cells·µL−1 | 309 (18.4) |
| Missing | 141 (8.4) |
| QoL-B RSS, median (IQR) | 63.0 (25.9) |
All data are Visit 2 (Baseline) data except where indicated. BMI: body mass index; MRC: Medical Research Council; BSI: Bronchiectasis Severity Index; QoL-B RSS: Quality of Life Questionnaire-Bronchiectasis Respiratory Symptom scores. #: n=1682.