Immunology

Impact of treatments targeting the GM-CSF pathway on the functions of human pulmonary macrophages
Hélène Salvator, Mathilde Zrounba, Marion Brollo, Stanislas Grassin-Delyle, Quentin Marquant, Emmanuel Naline, Louis-Jean Couderc, Antoine Magnan, Philippe Devillier

ERJ Open Research Mar 2022, 8 (suppl 8) 91; DOI: 10.1183/23120541.LSC-2022.91
Profiling systemic inflammation and neutrophil function in hospitalized patients with COVID19: results from PREDICT-COVID19
Merete Long, Holly R Keir, Yan Hui Giam, Andrew J M Howden, Alejandro J Brenes, Christina Rollings, Thomas Pembridge, Lilia Delgado, Hani Abo-Leyah, Rebecca C Hull, Amy Gilmour, Chloe Hughes, Rebecca Dowey, Helena Turton, Benjamin J M New, David W Connell, Hollian Richardson, Roger Thompson, Alison M Condliffe, Angus I Lamond, Diane M Cassidy, Amelia Shoemark, Doreen A Cantrell, James D Chalmers

ERJ Open Research Mar 2022, 8 (suppl 8) 130; DOI: 10.1183/23120541.LSC-2022.130
High-dimensional characterisation of the airway wall of paediatric patients with asthma and pre-school wheeze using Imaging Mass Cytometry
William Traves, Franz Puttur, Laura Yates, Sejal Saglani, Clare Lloyd

ERJ Open Research Mar 2022, 8 (suppl 8) 241; DOI: 10.1183/23120541.LSC-2022.241
Assessment of mucosal and systemic phagocytosis in Health Care Professionals (HCPs) in the post COVID-19 period
Nadezda Kryukova, Natal'Ya Abramova, Ekaterina Khromova, Svetlana Skhodova, Irina Bisheva, Dmitry Pakhomov, Aleksandra Vinnitskaya, Mikhail Kostinov, Irina Baranova, Oxana Svitich

ERJ Open Research Mar 2022, 8 (suppl 8) 208; DOI: 10.1183/23120541.LSC-2022.208
DNA-viruses modulates changes in B cells phenotype and auto-Abs in asthma.
Anna Konishcheva, Ospelnikova Tatyana, Skhodova Svetlana

ERJ Open Research Mar 2022, 8 (suppl 8) 221; DOI: 10.1183/23120541.LSC-2022.221
Lung surfactant lipids reduce the alternative activation and proliferation of alveolar macrophages induced by IL-4
Belén García-Fojeda, Carlos Minutti, Marianela Landoni, Paula Tenreiro, Cristina Casals

ERJ Open Research Mar 2022, 8 (suppl 8) 251; DOI: 10.1183/23120541.LSC-2022.251
Inflammatory blood neutrophils in COPD stem from activated bone marrow progenitors
Theodore Kapellos, Kevin Bassler, Wataru Fujii, Tal Pecht, Lorenzo Bonaguro, Izabela Galvao, Adem Saglam, Erica Dudkin, Amit Frishberg, Elena De Domenico, Arik Horne, Chantal Donovan, Richard Y. Kim, David Gallego-Ortega, Matthias Becker, Kristian Händler, Thomas Ulas, Jan Hasenauer, Carmen Pizarro, Phil M. Hansbro, Dirk Skowasch, Joachim L. Schultze

ERJ Open Research Mar 2022, 8 (suppl 8) 210; DOI: 10.1183/23120541.LSC-2022.210
Cigarette smoke alters macrophage mitochondrial iron handling in COPD
Lynne Faherty, Kihwan Kim, Elizabeth Perez, William Zhang, Suzanne Cloonan

ERJ Open Research Mar 2022, 8 (suppl 8) 227; DOI: 10.1183/23120541.LSC-2022.227
Interleukin-10 expressing regulatory B cells are decreased in blood of smokers and COPD patients
Merel Jacobs, Sven Verschraegen, Bihiyga Salhi, Jasper Anckaert, Pieter Mestdagh, Guy Brusselle, Ken Bracke

ERJ Open Research Mar 2022, 8 (suppl 8) 11; DOI: 10.1183/23120541.LSC-2022.11
Synergistic action of apoptotic cells and surfactant protein A in boosting IL-4-dependent alternative activation of alveolar macrophages.
Paula Tenreiro, Belen Garcia-Fojeda, Cristina Casals

ERJ Open Research Mar 2022, 8 (suppl 8) 245; DOI: 10.1183/23120541.LSC-2022.245

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