Best Practice & Research Clinical Endocrinology & Metabolism
Volume 23, Issue 6, December 2009, Pages 793-800
9Drugs that suppress TSH or cause central hypothyroidism
Section snippets
Glucocorticoids
Glucocorticoids have long been known to affect serum TSH levels in humans.*3, 4 Physiologic levels of hydrocortisone appear to play an important role in the diurnal variation of serum TSH levels with lower levels in the morning and higher levels at night.5, *6 Wilber and Utiger showed that high-dose glucocorticoids suppressed serum TSH in hypothyroid patients and normal subjects.3 This effect appeared to involve TSH secretion and was controlled at the level of the hypothalamus. Others have
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