The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: Thirty-sixth adult lung and heart–lung transplantation Report—2019; Focus theme: Donor and recipient size match
Section snippets
Data collection, conventions, and statistical methods
National and multinational organ and data exchange organizations and individual centers submit data to the International Society for Heart and Lung Transplantation International Thoracic Organ Transplant Registry. Since the Registry's inception, 481 heart transplant centers, 260 lung transplant centers, and 184 centers that perform combined heart-lung transplants have reported data to the Registry.1, 2, 3, 4 It is estimated that data submitted to the Registry represents approximately 75% of the
Focus theme methods: Donor and recipient size match
Although widely acknowledged as important in matching a donor with a recipient, there has been relatively little published on the impact of size matching on outcomes after lung and heart-lung transplantation. Most of the relatively small studies published so far suggest that recipients of oversized allografts experience either slightly better9, 10, 11, 12 or equivalent13, 14 short-term (primary graft dysfunction) and long-term (mortality) outcomes after lung transplantation. For this year's
Conclusions
The 2019 report presents important information regarding the global practice of lung and heart-lung transplantation. A history of donation after circulatory death has emerged as being associated with higher post-lung transplant survival at 10 years. Although numbers remain small, and different explanations for this finding are conceivable, the data presented here suggests that long-term survival after DCD lung transplantation is favorable. This report represents the most comprehensive
Disclosure statement
Kiran Khush serves as scientific adviser and speaker for CareDx, Inc; Luciano Potena serves as a speaker for Thermofisher, Sandoz, One Lambda, and Novartis, and is advisory board member for Qiagen and Novartis; Josef Stehlik serves as consultant for Medtronic and Abbott; Daniel Chambers received research funding from Astellas and Boeringher-Ingelheim; Joseph Rossano serves as consultant for Bayer, Novartis, Amgen, CSL Behring; Andreas Zuckermann serves on the speakers bureau of Paragonix,
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