ArticleContribution of mucus concentration and secreted mucins Muc5ac and Muc5b to the pathogenesis of muco-obstructive lung disease
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Published online: 20 July 2016
Author contributions A.L.-B., W.K.O., and R.C.B. designed the study; K.J.W. and A.S.V. maintained mouse colonies, generated experimental animals, and collected body weight and survival data; A.L.B. and K.J.W. performed phenotyping experiments involving BAL analyses (differential cell counts, microbiology, etc.) and tissue harvest; K.A.B. provided histological specimens; A.L.-B. performed mucin agarose western blots, histopathological, immunohistochemistry/immunofluorescence, and morphometric analyses; B.R.G. performed and analyzed the data for the MCC assay; C.M.E., provided Muc5ac−/− and Muc5b−/− mice and reviewed the manuscript; A.L.-B. analyzed the rest of the data, and wrote the manuscript. B.R.G., W.K.O., and R.C.B. contributed to interpretation of the data and reviewed the manuscript.
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W K O'Neal and R C Boucher: These authors contributed equally to this work.
An erratum to this article is available online at https://doi.org/10.1038/mi.2017.29.