Abstract
Introduction: Diagnostic utitilty of diaphragm ultrasound (B-mode) has been widely used. Diaphragmatic thickness fraction measurements (ΔTdi) have been reported to be useful in determination of lung hyperinflation in subjects with COPD. However, the clinical significane of diaphragm ultrasound for assessing the disease severity has been scarcely reported.
Aim: We aimed to compare diaphragmatic function between stage I/II and stage III/IV COPD patients based on the hypothesis that the latter group might have functional impairment than that of former one.
Material and Methods: We prospectively enrolled the stable COPD patients. We exclude congestive heart failure, asthma, active respiratory diseases (ie; acute exacerbation of COPD within two months prior to enrollment) and/or thoracic deformity. ΔTdi was calculated by the change in right diaphragm thickness between end-inspiration (Tdi-Insp) and end-expiration (Tdi-Exp) at supine position and ΔTdi% was defined as ΔTdi/Tdi end-expiratoin x100.
Results: Total of fourteen COPD patients (male 11, female 3) were enrolled whose of age was ranged from 61 to 87. Clinical findings includes Δtdi (%) and Tdi-Exp between stageI/II and stageIII/IV patients were comparable (Table1), but not for Tdi-Insp (median 2.7mm, IQR:1.9-3.0 vs median 2.0mm, IQR: 1.5-2.5, p=0.047). ROC curve for preferable Tdi-Insp value for discriminating stageI/II from stageIII/IV was 2.63mm with a sensitivity of 71.4%, specificity of 100% (AUC 0.816, 95%CI: 0.567-1.0, p=0.048)(Fig.1).
Conclusion: Diaphragm ultrasound by using Tdi-Insp might be a simple and high diagnostic yield for suspecting of early stage of COPD patients.
Footnotes
Cite this article as: European Respiratory Journal 2019; 54: Suppl. 63, OA5366.
This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).
- Copyright ©the authors 2019