Chest
Clinical InvestigationsASTHMAValidation of a Standardized Version of the Asthma Quality of Life Questionnaire
Section snippets
Formulation of the Five Generic Activities
Our aim was to formulate five generic activity questions that would cover the activities that are most frequently identified by asthma patients as being the most troublesome in their day-to-day lives. In addition, we wanted to ensure that the balance of the five questions (physical, social, occupational) reflects the frequency with which the activities are identified by patients. We reviewed the original item reduction data from the development of the AQLQ1 and a number of clinical trial
Results
All 40 patients completed the first three assessments; 1 patient failed to return for the final visit. Demographic data are shown in Table 2.
Discussion
The results of this study provide evidence that the AQLQ(S) is a valid instrument for measuring health-related quality of life in adults with asthma. We evaluated validity in two ways: first, by determining the level of concordance (agreement) between the AQLQ(S) and the AQLQ (criterion validity); and, second, by comparing the measurement properties of the two instruments (construct validity).
The concordance analysis showed that the mean score for the activity domain of the AQLQ(S) was
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