Hypersensitivity Pneumonitis Induced by Konjak Flour and Powdered Hijikia fusiforme

Shunji TAJIMA; Hiroaki KON; Katsuhisa OSHIKAWA; Masashi BANDO; Shoji OHNO; Yukihiko SUGIYAMA

doi:10.2169/internalmedicine.42.846

Hypersensitivity Pneumonitis Induced by Konjak Flour and Powdered Hijikia fusiforme

Shunji TAJIMA, Hiroaki KON, Katsuhisa OSHIKAWA, Masashi BANDO, Shoji OHNO, Yukihiko SUGIYAMA

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Keywords: Konnyaku manufacturer's lung, Amorphophalus konjak, Hijikia fusiforme, peripheral blood lymphocyte stimulation test, double immunodiffusion test

JOURNAL FREE ACCESS

2003 Volume 42 Issue 9 Pages 846-849

DOI https://doi.org/10.2169/internalmedicine.42.846

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Abstract

This is a report of a patient with occupational hypersensitivity pneumonitis (HP) caused by Konjak flour and powdered Hijikia fusiforme. A 56-year-old man had worked as a Konnyaku manufacturer for 38 years, and suffered from dyspnea on exertion. Konnyaku is a paste made from Konjak flour, powdered Hijikia fusiforme, quicklime, and powdered scallop shell. The diagnosis of HP was confirmed immunologically by the detection of serum precipitins to powdered Hijikia fusiforme, and by the positive result of in vitro lymphocytic proliferative response for Konjak flour using peripheral blood lymphocytes. To our knowledge, this is the first case report of Konnyaku manufacturer's lung.
(Internal Medicine 42: 846-849, 2003)

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