Evaluation of Binax NOW, an assay for the detection of pneumococcal antigen in urine samples, performed among pediatric patients

S F Dowell; R L Garman; G Liu; O S Levine; Y H Yang

doi:10.1086/319205

Evaluation of Binax NOW, an assay for the detection of pneumococcal antigen in urine samples, performed among pediatric patients

Clin Infect Dis. 2001 Mar 1;32(5):824-5. doi: 10.1086/319205. Epub 2001 Feb 23.

Authors

S F Dowell¹, R L Garman, G Liu, O S Levine, Y H Yang

Affiliation

¹ Respiratory Disease Branch, Division of Bacterial and Mycotic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA. sfd2@cdc.gov

PMID: 11229853
DOI: 10.1086/319205

Abstract

In our evaluation of a new assay for the detection of pneumococcal antigen in urine (Binax NOW; Binax), the test result was no more likely to be positive among 88 children with radiographically confirmed pneumonia than among 198 control subjects; however, it was significantly more likely to be positive among children who were nasopharyngeal carriers of pneumococci. This test is not likely to be useful for distinguishing children with pneumococcal pneumonia from those who are merely colonized.

Publication types

Evaluation Study

MeSH terms

Antigens, Bacterial / urine*
Carrier State / diagnosis*
Carrier State / microbiology
Child, Preschool
Humans
Infant
Nasopharynx / microbiology*
Pneumonia, Pneumococcal / diagnosis*
Pneumonia, Pneumococcal / diagnostic imaging
Pneumonia, Pneumococcal / microbiology
Radiography
Reagent Kits, Diagnostic
Sensitivity and Specificity
Streptococcus pneumoniae / immunology
Streptococcus pneumoniae / isolation & purification*
Urine / microbiology*

Substances

Antigens, Bacterial
Reagent Kits, Diagnostic