Abstract
Primary ciliary dyskinesia (PCD) is characterized by ultra-structural defects of the cilia. In this report, we describe the long-term use of nebulized dornase alfa in two siblings with PCD. This is the first report of long-term use of dornase alfa in PCD.
MeSH terms
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Adolescent
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Deoxyribonuclease I / administration & dosage*
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Forced Expiratory Volume / drug effects
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Humans
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Kartagener Syndrome / drug therapy*
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Long-Term Care / methods
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Male
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Nebulizers and Vaporizers
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Treatment Outcome
Substances
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DNASE1 protein, human
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Deoxyribonuclease I