Genetic diversity within Mycobacterium tuberculosis complex impacts on the accuracy of genotypic pyrazinamide drug-susceptibility assay

Affiliations

• ¹ Department of Medicine, University of Cambridge, Cambridge, United Kingdom. Electronic address: cuk21@cam.ac.uk.
• ² Genomics and Health Unit, FISABIO, Valencia, Spain; CIBER (Centros de Investigación Biomédica en Red) in Epidemiology and Public Health, Spain.
• ³ Molecular Mycobacteriology, Borstel, Germany; German Centre for Infection Research, Research Centre Borstel, Borstel, Germany.
• ⁴ Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland; University of Basel, Basel, Switzerland.
• ⁵ Department of Medicine, University of Cambridge, Cambridge, United Kingdom; Clinical Microbiology and Public Health Laboratory, Public Health England, Cambridge, United Kingdom; Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, United Kingdom.