Chronic ivacaftor treatment: getting F508del-CFTR into more trouble?

Affiliations

• ¹ Department of Translational Pulmonology, Translational Lung Research Center Heidelberg (TLRC), University of Heidelberg, Member of the German Center for Lung Research (DZL), Im Neuenheimer Feld 350, 69120, Heidelberg, Germany; Division of Pediatric Pulmonology & Cystic Fibrosis Center, University of Heidelberg, Member of the German Center for Lung Research (DZL), Heidelberg, Germany. Electronic address: Marcus.Mall@med.uni-heidelberg.de.
• ² School of Physiology and Pharmacology, University of Bristol, Medical Sciences Building, University Walk, Bristol BS8 1TD, Bristol, UK. Electronic address: D.N.Sheppard@bristol.ac.uk.