Children Hospitalized with Rhinovirus Bronchiolitis Have Asthma-Like Characteristics

Jonathan M Mansbach; Sunday Clark; Stephen J Teach; James E Gern; Pedro A Piedra; Ashley F Sullivan; Janice A Espinola; Carlos A Camargo Jr

doi:10.1016/j.jpeds.2016.01.041

Children Hospitalized with Rhinovirus Bronchiolitis Have Asthma-Like Characteristics

J Pediatr. 2016 May:172:202-204.e1. doi: 10.1016/j.jpeds.2016.01.041. Epub 2016 Feb 11.

Authors

Jonathan M Mansbach¹, Sunday Clark², Stephen J Teach³, James E Gern⁴, Pedro A Piedra⁵, Ashley F Sullivan⁶, Janice A Espinola⁶, Carlos A Camargo Jr⁶

Affiliations

¹ Department of Medicine, Boston Children's Hospital, Harvard Medical School, Boston, MA.
² Department of Emergency Medicine, Weill Cornell Medical College, New York, NY.
³ Department of Pediatrics, Children's National Health System, George Washington University School of Medicine and Health Sciences, Washington, DC.
⁴ Department of Pediatrics and Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI.
⁵ Departments of Molecular Virology and Microbiology, and Pediatrics, Baylor College of Medicine, Houston, TX.
⁶ Department of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA.

Abstract

Children with bronchiolitis often are considered a homogeneous group. However, in a multicenter, prospective study of 2207 young children hospitalized for bronchiolitis, we found that children with respiratory syncytial virus detected differ from those with rhinovirus detected; the latter patients resemble older children with asthma, including more frequent treatment with corticosteroids.

Publication types

Multicenter Study
Observational Study
Research Support, N.I.H., Extramural

MeSH terms

Asthma / diagnosis*
Bronchiolitis, Viral / diagnosis*
Diagnosis, Differential
Female
Hospitalization
Humans
Infant
Male
Picornaviridae Infections / diagnosis*
Prospective Studies
Respiratory Syncytial Virus Infections / diagnosis*
Respiratory Syncytial Viruses
Rhinovirus

Grants and funding

U01 AI067693/AI/NIAID NIH HHS/United States