Abstract
Two indices of alveolar epithelial permeability were derived in man by a non-invasive method. The rate of transfer of 99mTc DTPA (diethylenetriamine penta-acetate) from the lung into the blood was measured and a significantly greater (P less than 0.001) transfer rate was found in symptomless cigarette smokers compared with non-smokers.
MeSH terms
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Adult
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Aerosols
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Biological Availability
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Capillary Permeability*
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Half-Life
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Humans
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Isotope Labeling
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Male
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Metabolic Clearance Rate
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Middle Aged
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Pentetic Acid / administration & dosage
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Pentetic Acid / metabolism
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Pulmonary Alveoli / blood supply*
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Smoking / physiopathology*
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Technetium
Substances
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Aerosols
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Technetium
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Pentetic Acid