Chronic obstructive pulmonary disease (COPD) is a global health problem, and since 2001,
the Global Initiative for Chronic Obstructive Lung Disease (GOLD) has published its strategy …

Precision medicine is a patient-specific approach that integrates all relevant clinical, genetic
and biological information in order to optimise the therapeutic benefit relative to the …

Chronic obstructive pulmonary disease (COPD) is characterised by an inappropriate/excessive
inflammatory response of the lungs to respiratory pollutants, mainly tobacco smoking. …

Background The effect of obstructive sleep apnoea-hypopnoea as a cardiovascular risk factor
and the potential protective effect of its treatment with continuous positive airway pressure (…

This Executive Summary of the Global Strategy for the Diagnosis, Management, and Prevention
of COPD, Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2017 report …

Background Chronic obstructive pulmonary disease (COPD) is thought to result from an
accelerated decline in forced expiratory volume in 1 second (FEV 1 ) over time. Yet it is possible …

Background Chronic obstructive pulmonary disease (COPD) is a complex condition with
pulmonary and extra-pulmonary manifestations. This study describes the heterogeneity of …

Rationale: Understanding normal lung development and aging in health and disease, both in
men and in women, is essential to interpreting any therapeutic intervention. Objectives: We …

Background A key feature of chronic obstructive pulmonary disease (COPD) is an accelerated
rate of decline in forced expiratory volume in 1 second (FEV 1 ), but data on the variability …

Chronic obstructive pulmonary disease (COPD) represents an increasing burden throughout
the world. COPD-related mortality is probably underestimated because of the difficulties …