EAACI IG Biologicals task force paper on the use of biologic agents in allergic disorders

O Boyman, C Kaegi, M Akdis, S Bavbek, A Bossios… - Allergy, 2015 - Wiley Online Library
Biologic agents (also termed biologicals or biologics) are therapeutics that are synthesized
by living organisms and directed against a specific determinant, for example, a cytokine or …

Viruses and bacteria in acute asthma exacerbations – A GA2LEN‐DARE* systematic review

…, C Almqvist, A Bruno, S Bonini, L Bont, A Bossios… - Allergy, 2011 - Wiley Online Library
To cite this article: Papadopoulos NG, Christodoulou I, Rohde G, Agache I, Almqvist C, Bruno
A, Bonini S, Bont L, Bossios A, Bousquet J, Braido F, Brusselle G, Canonica GW, Carlsen …

New biological treatments for asthma and skin allergies

S Eyerich, M Metz, A Bossios, K Eyerich - Allergy, 2020 - Wiley Online Library
Allergies are typically endemic, complex and heterogeneous diseases with a high impact at
quality of life. Mechanistically, type 2 immune responses involving eosinophil and basophil …

[HTML][HTML] Human saliva, plasma and breast milk exosomes contain RNA: uptake by macrophages

…, M Eldh, P Torregrosa Paredes, A Bossios… - Journal of translational …, 2011 - Springer
Background Exosomes are 30-100 nm membrane vesicles of endocytic origin produced by
numerous cells. They can mediate diverse biological functions, including antigen …

Association of rhinovirus infection with increased disease severity in acute bronchiolitis

…, M Moustaki, M Tsolia, A Bossios… - American journal of …, 2002 - atsjournals.org
Respiratory syncytial virus (RSV) is the major pathogen responsible for acute bronchiolitis
in infancy. However, evaluation of the relative importance of rhinovirus or multiple viral …

Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells

H Valadi, K Ekström, A Bossios, M Sjöstrand, JJ Lee… - Nature cell …, 2007 - nature.com
Exosomes are vesicles of endocytic origin released by many cells. These vesicles can mediate
communication between cells, facilitating processes such as antigen presentation. Here, …

Etiology of community-acquired pneumonia in hospitalized school-age children: evidence for high prevalence of viral infections

MN Tsolia, S Psarras, A Bossios, H Audi… - Clinical infectious …, 2004 - academic.oup.com
Background. Community-acquired pneumonia (CAP) in young children is most commonly
associated with viral infections; however, the role of viruses in CAP of school-age children is …

Considerations on biologicals for patients with allergic disease in times of the COVID‐19 pandemic: an EAACI statement

…, I Agache, CA Akdis, M Akdis, S Bavbek, A Bossios… - Allergy, 2020 - Wiley Online Library
The outbreak of the SARS‐CoV‐2‐induced coronavirus disease 2019 (COVID‐19) pandemic
re‐shaped doctor‐patient interaction and challenged capacities of healthcare systems. It …

MicroRNA-155 is essential for TH2-mediated allergen-induced eosinophilic inflammation in the lung

…, S Alawieh, Y Lu, M Sjöstrand, A Bossios… - Journal of Allergy and …, 2014 - Elsevier
Background Allergic asthma is a chronic disease of the conducting airways characterized by
T H 2 inflammation and tissue remodeling after exposure to inhaled allergens. Although the …

Characterization of mRNA and microRNA in human mast cell-derived exosomes and their transfer to other mast cells and blood CD34 progenitor cells

…, M Sjöstrand, C Malmhäll, A Bossios… - Journal of …, 2012 - Taylor & Francis
Background: Exosomes are nanosized vesicles of endocytic origin that are released into the
extracellular environment by many different cells. It has been shown that exosomes from …