[HTML][HTML] Physical, cognitive, and mental health impacts of COVID-19 after hospitalisation (PHOSP-COVID): a UK multicentre, prospective cohort study
…, H McAuley, EM Harrison, A Shikotra… - The Lancet …, 2021 - thelancet.com
Background The impact of COVID-19 on physical and mental health and employment after
hospitalisation with acute disease is not well understood. The aim of this study was to …
hospitalisation with acute disease is not well understood. The aim of this study was to …
Periostin is a systemic biomarker of eosinophilic airway inflammation in asthmatic patients
…, S Mosesova, LC Wu, OD Solberg, A Shikotra… - Journal of Allergy and …, 2012 - Elsevier
BACKGROUND: Eosinophilic airway inflammation is heterogeneous in asthmatic patients.
We recently described a distinct subtype of asthma defined by the expression of genes …
We recently described a distinct subtype of asthma defined by the expression of genes …
TH2 and TH17 inflammatory pathways are reciprocally regulated in asthma
Increasing evidence suggests that asthma is a heterogeneous disorder regulated by distinct
molecular mechanisms. In a cross-sectional study of asthmatics of varying severity (n = 51), …
molecular mechanisms. In a cross-sectional study of asthmatics of varying severity (n = 51), …
Increased expression of immunoreactive thymic stromal lymphopoietin in patients with severe asthma
A Shikotra, DF Choy, CM Ohri, E Doran, C Butler… - Journal of allergy and …, 2012 - Elsevier
BACKGROUND: Thymic stromal lymphopoietin (TSLP) is a cytokine implicated in the
pathophysiology of asthma through 2 distinct pathways: a TSLP–OX40 ligand (OX40L)–T cell axis …
pathophysiology of asthma through 2 distinct pathways: a TSLP–OX40 ligand (OX40L)–T cell axis …
[HTML][HTML] Acute blood biomarker profiles predict cognitive deficits 6 and 12 months after COVID-19 hospitalization
…, M Richardson, O Elneima, HJC McAuley, A Shikotra… - Nature medicine, 2023 - nature.com
Post-COVID cognitive deficits, including ‘brain fog’, are clinically complex, with both objective
and subjective components. They are common and debilitating, and can affect the ability to …
and subjective components. They are common and debilitating, and can affect the ability to …
[HTML][HTML] Clinical characteristics with inflammation profiling of long COVID and association with 1-year recovery following hospitalisation in the UK: a prospective …
…, O Elneima, HJC McAuley, A Shikotra… - The Lancet …, 2022 - thelancet.com
Background No effective pharmacological or non-pharmacological interventions exist for
patients with long COVID. We aimed to describe recovery 1 year after hospital discharge for …
patients with long COVID. We aimed to describe recovery 1 year after hospital discharge for …
Residual lung abnormalities after COVID-19 hospitalization: interim analysis of the UKILD post–COVID-19 study
…, MG Semple, M Sereno, A Shikotra… - American journal of …, 2023 - atsjournals.org
Rationale: Shared symptoms and genetic architecture between coronavirus disease (COVID-19)
and lung fibrosis suggest severe acute respiratory syndrome coronavirus 2 (SARS-CoV-…
and lung fibrosis suggest severe acute respiratory syndrome coronavirus 2 (SARS-CoV-…
Physical, cognitive and mental health impacts of COVID-19 following hospitalisation–a multi-centre prospective cohort study
…, RA Evans, H McAuley, EM Harrison, A Shikotra… - MedRxiv, 2021 - medrxiv.org
Background The impact of COVID-19 on physical and mental health, and employment
following hospitalisation is poorly understood. Methods PHOSP-COVID is a multi-centre, UK, …
following hospitalisation is poorly understood. Methods PHOSP-COVID is a multi-centre, UK, …
[HTML][HTML] Multiorgan MRI findings after hospitalisation with COVID-19 in the UK (C-MORE): a prospective, multicentre, observational cohort study
Introduction The multiorgan impact of moderate to severe coronavirus infections in the post-acute
phase is still poorly understood. We aimed to evaluate the excess burden of multiorgan …
phase is still poorly understood. We aimed to evaluate the excess burden of multiorgan …
Effects of sleep disturbance on dyspnoea and impaired lung function following hospital admission due to COVID-19 in the UK: a prospective multicentre cohort study
…, JT Scott, M Sereno, AM Shah, A Shikotra… - The Lancet …, 2023 - thelancet.com
Background Sleep disturbance is common following hospital admission both for COVID-19
and other causes. The clinical associations of this for recovery after hospital admission are …
and other causes. The clinical associations of this for recovery after hospital admission are …