Histamine signaling and metabolism identify potential biomarkers and therapies for lymphangioleiomyomatosis
…, E Billett, E Radzikowska, Á Casanova… - EMBO Molecular …, 2021 - embopress.org
Inhibition of mTOR is the standard of care for lymphangioleiomyomatosis (LAM). However,
this therapy has variable tolerability and some patients show progressive decline of lung …
this therapy has variable tolerability and some patients show progressive decline of lung …
Melatonin and steroid hormones activate intermembrane Cu, Zn-superoxide dismutase by means of mitochondrial cytochrome P450
P Iñarrea, A Casanova, MA Alava, M Iturralde… - Free Radical Biology …, 2011 - Elsevier
Melatonin and steroid hormones are cytochrome P450 (CYP or P450; EC 1.14.14.1)
substrates that have antioxidant properties and mitochondrial protective activities. The …
substrates that have antioxidant properties and mitochondrial protective activities. The …
Mitochondrial Complex Enzyme Activities and Cytochrome c Expression Changes in Multiple Sclerosis
…, R Alarcia, MA Alava, JL Capablo, A Casanova… - Molecular …, 2014 - Springer
Blood platelets have been widely proposed as biomarkers in studies of mitochondrial function
and aging-related and neurodegenerative diseases. Defects in mitochondrial function …
and aging-related and neurodegenerative diseases. Defects in mitochondrial function …
Upconverting carbon nanodots from ethylenediaminetetraacetic acid (EDTA) as near‐infrared activated phototheranostic agents
…, MM Encabo‐Berzosa, A Casanova… - … A European Journal, 2019 - Wiley Online Library
This work describes the synthesis of nitrogen‐doped carbon nanodots (CNDs) synthesized
from ethylenediaminetetraacetic acid (EDTA) as a precursor and their application as …
from ethylenediaminetetraacetic acid (EDTA) as a precursor and their application as …
[HTML][HTML] Lymphangioleiomyomatosis biomarkers linked to lung metastatic potential and cell stemness
…, C Valenzuela, J Ancochea, A Xaubet, Á Casanova… - PLoS …, 2015 - journals.plos.org
Lymphangioleiomyomatosis (LAM) is a rare lung-metastasizing neoplasm caused by the
proliferation of smooth muscle-like cells that commonly carry loss-of-function mutations in either …
proliferation of smooth muscle-like cells that commonly carry loss-of-function mutations in either …
[HTML][HTML] Cyclooxygenase-2 polymorphisms confer susceptibility to sarcoidosis but are not related to prognosis
…, JF Guerra, FJG Hernandez, A Casanova… - Respiratory …, 2009 - Elsevier
BACKGROUND: The aim of this multicenter study was to investigate the relationship between
single nucleotide polymorphisms (SNPs) of the cyclooxygenase-2 (COX2) gene and …
single nucleotide polymorphisms (SNPs) of the cyclooxygenase-2 (COX2) gene and …
[HTML][HTML] Janus dendrimers to assess the anti-HCV activity of molecules in cell-assays
…, JE Egido, R Clavería-Gimeno, Á Casanova… - Pharmaceutics, 2020 - mdpi.com
The use of nanocarriers has been revealed as a valid strategy to facilitate drug bioavailability,
and this allows for expanding the drug libraries for the treatment of certain diseases such …
and this allows for expanding the drug libraries for the treatment of certain diseases such …
Lymphangioleiomyomatosis treatment with sirolimus
Á Casanova, RM Girón, O Acosta, M Barrón… - Archivos de …, 2011 - Elsevier
Lymphangioleiomyomatosis (LAM) is a rare lung disease that predominantly affects young
females and generally progresses to respiratory failure. There is not sufficient evidence to …
females and generally progresses to respiratory failure. There is not sufficient evidence to …
[HTML][HTML] Study of breast cancer incidence in patients of lymphangioleiomyomatosis
…, SR Johnson, Y Inoue, M Hirose, Á Casanova… - Breast Cancer Research …, 2016 - Springer
Molecular evidence has linked the pathophysiology of lymphangioleiomyomatosis (LAM) to
that of metastatic breast cancer. Following on this observation, we assessed the association …
that of metastatic breast cancer. Following on this observation, we assessed the association …
Effects of allergen-specific immunotherapy on peripheral blood regulatory T cells and serum concentrations of cytokines and immunoglobulins in horses with allergic …
…, MT Verde, T Conde, D Pereboom, Á Casanova… - International …, 2019 - Elsevier
The aim of this study was to assess the effect of allergen-specific immunotherapy (ASIT) on
the immunological responses of horses. Blood samples were taken from thirty-two horses …
the immunological responses of horses. Blood samples were taken from thirty-two horses …