Abbreviations: ACE angiotensin-converting enzyme; ACP American College of Physicians;
A/D antihistamine/decongestant; ATS American Thoracic Society; BPC bronchoprovocation …

Objectives: To review relevant literature and present evidence-based guidelines to assist
general and specialist medical practitioners in the evaluation and management of children who …

Chronic cough is globally prevalent across all age groups. This disorder is challenging to treat
because many pulmonary and extrapulmonary conditions can present with chronic cough…

Objective To evaluate the use of an adult-based algorithmic approach to chronic cough in a
cohort of children with a history of > 3 weeks of cough and to describe the etiology of chronic …

Background We performed systematic reviews using the population, intervention, comparison,
outcome (PICO) format to answer the following key clinical question: Are the CHEST 2006 …

Bronchopulmonary C-fibers and a subset of mechanically sensitive, acid-sensitive myelinated
sensory nerves play essential roles in regulating cough. These vagal sensory nerves …

Background Unexplained chronic cough (UCC) causes significant impairments in quality of
life. Effective assessment and treatment approaches are needed for UCC. Methods This …

Background Gastroesophageal reflux disease (GORD) is said to be the causative factor in up
to 41% of adults with chronic cough. Treatment for GORD includes conservative measures (…

The role of persistent and recurrent bacterial infection of the conducting airways (endobronchial
infection) in the causation of chronic respiratory symptoms, particularly chronic wet …

Background Mycoplasma pneumoniae (M. pneumoniae) is widely recognised as an
important cause of community‐acquired lower respiratory tract infection (LRTI) in children. …