[HTML][HTML] The two-stage placental model of preeclampsia: An update

AC Staff - Journal of reproductive immunology, 2019 - Elsevier
Early-onset preeclampsia has been linked to poor placentation and fetal growth restriction,
whereas late-onset preeclampsia was suggested to result from maternal factors. We have …

[HTML][HTML] Predictive value of the sFlt-1: PlGF ratio in women with suspected preeclampsia

…, F Chantraine, M Vatish, AC Staff… - … England Journal of …, 2016 - Mass Medical Soc
Background The ratio of soluble fms-like tyrosine kinase 1 (sFlt-1) to placental growth factor (PlGF)
is elevated in pregnant women before the clinical onset of preeclampsia, but its …

Redefining preeclampsia using placenta-derived biomarkers

AC Staff, SJ Benton, P von Dadelszen, JM Roberts… - …, 2013 - Am Heart Assoc
Compared with the nonpregnant state, normal pregnancy is characterized by a low-grade
systemic inflammatory response, which is further enhanced in preeclampsia. 17 It is important …

Are obstetric anal sphincter ruptures preventable?–large and consistent rupture rate variations between the Nordic countries and between delivery units in Norway

K Laine, W Rotvold, AC Staff - Acta obstetricia et gynecologica …, 2013 - Wiley Online Library
… for manual perineal protection for the delivery staff, and five units have published their data
(… of delivering staff, contamination of methods in different study arms and blinding (of staff or …

[HTML][HTML] Failure of physiological transformation and spiral artery atherosis: their roles in preeclampsia

AC Staff, HE Fjeldstad, IK Fosheim, K Moe… - American journal of …, 2022 - Elsevier
Physiological transformation with remodeling of the uteroplacental spiral arteries is key to a
successful placentation and normal placental function. It is an intricate process that involves, …

The 2021 International Society for the Study of Hypertension in Pregnancy classification, diagnosis & management recommendations for international practice

…, J Myers, LC Poon, S Rana, S Saito, AC Staff… - Pregnancy …, 2022 - Elsevier
All units managing hypertensive pregnant women should maintain and review uniform
departmental management protocols and conduct regular audits of maternal & fetal outcomes. …

Preeclampsia, biomarkers, syncytiotrophoblast stress, and placental capacity

CWG Redman, AC Staff - American journal of obstetrics and gynecology, 2015 - Elsevier
The maternal syndrome of preeclampsia is mediated by dysfunctional syncytiotrophoblast (STB).
When this is stressed by uteroplacental malperfusion, its signaling to the mother …

Syncytiotrophoblast stress in preeclampsia: the convergence point for multiple pathways

CWG Redman, AC Staff, JM Roberts - American journal of obstetrics and …, 2022 - Elsevier
Preeclampsia evolves in 2 stages: a placental problem that generates signals to the mother
to cause a range of responses that comprise the second stage (preeclampsia syndrome). …

Learning from the placenta: acute atherosis and vascular remodeling in preeclampsia–novel aspects for atherosclerosis and future cardiovascular health

AC Staff, R Dechend, R Pijnenborg - Hypertension, 2010 - Am Heart Assoc
Preeclampsia is a common and potentially lethal pregnancy complication for women and
offspring. Women who develop preeclampsia also run a long-term augmented risk of …

Early food intervention and skin emollients to prevent food allergy in young children (PreventADALL): a factorial, multicentre, cluster-randomised trial

…, IC Olsen, K Rudi, CM Saunders, MK Skram, AC Staff… - The Lancet, 2022 - thelancet.com
Background Primary prevention of food allergy by early introduction of allergenic foods
seems promising. We aimed to determine whether early food introduction or the application of …